Effects of haemodialysis on Hemoglobin and red cell indices in chronic kidney disease patients at a tertiary health care institute

Abstract

Background: Chronic kidney disease (CKD) is a global health problem, with very high cost of care and greater burden particularly in developing countries like India.Material and Method: This prospective observational study of effects on hemoglobin and red cell indices in CKD before and after hemodialysis conducted on 150 CKD patients in SRM Medical College Hospital & Research Centre.Results: The most frequent morphologic features were normochromic-normocytic (78.7%), microcytic hypochromic (14.7%), macrocytic (3.3%) and dimorphic (3.3.%). Haemoglobin (Hb) levels and platelets counts are significantly reduced in post dialysis with a mean level of Hb 8.7 when compared to pre dialysis mean value of 7.78g/dL. There was a significant increase in MCV, with decrease in MCH and MCHC in the post dialysis values compared to pre dialysis.Conclusion: These hematological abnormalities expose CKD patients to higher risk of anemia-related complications. The present investigation might help clinicians to initiate precautions before and after dialysis procedures.