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Fetal Alcohol Spectrum Disorders: A Review of the Neurobehavioral Deficits Associated With Prenatal Alcohol Exposure

Alcoholism Clinical and Experimental Research · 2019 · Vol. 43(6) · pp. 1046–1062
Sarah N. MattsonGemma A. BernesLauren R. Doyle

Abstract

In utero alcohol exposure can disrupt the development of the fetal brain and result in a wide range of neurobehavioral outcomes collectively known as fetal alcohol spectrum disorders (FASD). This paper provides a comprehensive review of the cognitive and behavioral outcomes of prenatal alcohol exposure, including domains of general intelligence, executive functioning, language development, learning and memory, adaptive functioning, academic performance, and concurrent psychopathology. In addition, the current status of the neurobehavioral profile of FASD and its potential as a diagnostic tool will be discussed.

Prenatal Substance Exposure EffectsBirth, Development, and HealthNeonatal Health and BiochemistryFetal alcoholPrenatal alcohol exposureAlcoholPrenatal exposureFetal alcohol syndromeFetal Alcohol Spectrum DisorderMedicinePsychiatryFetusPsychology

MeSH terms

AnimalsBrainChildChild BehaviorCognitionFemaleHumansPregnancyPrenatal Exposure Delayed EffectsPrevalenceFetal Alcohol Spectrum Disorders

Funding

  • National Institute on Alcohol Abuse and Alcoholism
Citations
426
FWCI
61.23
field-weighted impact
References
176
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100%
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References
Executive Functioning in Children With Heavy Prenatal Alcohol Exposure
Alcoholism Clinical and Experimental Research · 1999 · 373 citations
Neuropsychological Deficits in Adolescents with Fetal Alcohol Syndrome: Clinical Findings
Alcoholism Clinical and Experimental Research · 1998 · 320 citations
Moderate Prenatal Alcohol Exposure: Effects on Child IQ and Learning Problems at Age 7 1/2 Years
Alcoholism Clinical and Experimental Research · 1990 · 548 citations
Brain dysmorphology in individuals with severe prenatal alcohol exposure
Developmental Medicine & Child Neurology · 2001 · 506 citations
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