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Antioxidant Activities of Quercetin and Its Complexes for Medicinal Application

Molecules · 2019 · Vol. 24(6) · pp. 1123–1123
Dong XuMeng-Jiao HuYan-Qiu WangYuan‐Lu Cui

Abstract

Quercetin is a bioactive compound that is widely used in botanical medicine and traditional Chinese medicine due to its potent antioxidant activity. In recent years, antioxidant activities of quercetin have been studied extensively, including its effects on glutathione (GSH), enzymatic activity, signal transduction pathways, and reactive oxygen species (ROS) caused by environmental and toxicological factors. Chemical studies on quercetin have mainly focused on the antioxidant activity of its metal ion complexes and complex ions. In this review, we highlight the recent advances in the antioxidant activities, chemical research, and medicinal application of quercetin.

Free Radicals and AntioxidantsPhytochemicals and Antioxidant ActivitiesComputational Drug Discovery MethodsAntioxidantQuercetinReactive oxygen speciesChemistryGlutathioneBiochemistryTraditional medicineEnzymePharmacologyBiology

MeSH terms

AntioxidantsCatalaseGlutathioneQuercetinStructure-Activity RelationshipSuperoxide DismutaseSignal TransductionReactive Oxygen SpeciesOxidative Stress

Funding

  • National Natural Science Foundation of China
Citations
1,257
FWCI
61.14
field-weighted impact
References
112
Percentile
100%
vs. same field & year
Citations per year
References
Health effects of quercetin: From antioxidant to nutraceutical
European Journal of Pharmacology · 2008 · 2,023 citations
Synthesis, characterization and antioxidant activity copper–quercetin complex
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · 2008 · 324 citations
Antioxidant and Oxidative Stress: A Mutual Interplay in Age-Related Diseases
Frontiers in Pharmacology · 2018 · 1,111 citations
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