review Open AccessTop 1% cited

Efficacy of anti‐inflammatory treatment on major depressive disorder or depressive symptoms: meta‐analysis of clinical trials

Acta Psychiatrica Scandinavica · 2019 · Vol. 139(5) · pp. 404–419

Ole Köhler‐Forsberg✉(Aarhus University Hospital)Cecilie N. Lydholm(Copenhagen University Hospital)Carsten Hjorthøj(University of Copenhagen)Merete Nordentoft(Copenhagen University Hospital)Ole Mors(Aarhus University Hospital)Michael E. Benros(Copenhagen University Hospital)

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Abstract

Anti-inflammatory agents improved antidepressant treatment effects. Future RCTs need to include longer follow-up, identify optimal doses and subgroups of patients that can benefit from anti-inflammatory intervention.

Tryptophan and brain disorders Health, psychology, and well-being Stress Responses and CortisolMeta-analysisMajor depressive disorderClinical trialDepressive symptomsPsychiatryDepression (economics)MedicinePsychologyInternal medicineClinical psychology

MeSH terms

PioglitazoneAdolescentAdultAgedAnti-Inflammatory AgentsAnti-Bacterial AgentsAntidepressive AgentsMajor Depressive DisorderDepressive Disorder, MajorFemaleGlucocorticoidsHumansHypoglycemic AgentsMaleMiddle Aged

Citations

409

FWCI

14.55

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