A prospective control study evaluating pregnancy outcome in PCOS patients: The bottom line truth of modern lifestyle

Abstract

Introduction: PCOS are at the risk of pregnancy complications such as Gestational Diabetes Mellitus (GDM) Hypertensive complications. Medical interventions that improve insulin sensitivity appear to have a positive impact on both early and late pregnancy complications in women with PCOS. Thus, the objective of this study is to compare the pregnancy outcome in PCOS women with normal women and to study the incidence of pregnancy complications such as spontaneous abortions, preterm labour, gestational diabetes, gestational hypertension, preeclampsia, pregnancy and neonatal outcome in women with PCOS & to compare the mode of conception, need of reproductive assistance. Methodology: This study was conducted in the department of Obstetrics and Gynecology, SMS Medical College in 80 pregnant women attending the antenatal clinic, satisfying the inclusion criteria. It was a prospective comparative study. The normal pregnant women, those who attended regular antenatal clinic during the same period and without medical illness such as diabetes mellitus, hypertension and thyroid disease were used as the control group. Result: Present study conducted on a total of 80 pregnant women, 40 of who were among the women who had a history of PCOS (i.e. either in the form of scan or positive blood parameters). Age and parity of both the groups were comparable. We noted that 50% women needed help in conceiving in form of ovulation induction, in vitro fertilization & intrauterine insemination as compared to only 12% in normal women group which is statistically significant (p