Comparative study of various modalities of treatment in uncomplicated amoebic liver abscess

Abstract

Background: Amoebic liver abscess is the most frequent extra-intestinal manifestation of Entamoeba histolytica infection. Aims and Objectives: To compare the various modalities of treatment in uncomplicated amoebic liver abscess. Materials & Methods: This prospective and randomized trial was carried out in the Surgery Department of M.L.N. Medical College, Allahabad, from 1st August, 2016 to 30th July, 2018. Total 96 patients with history and clinical examination suggestive of amoebic liver abscess attending surgical opd and those coming for follow up in outpatient department at regular intervals were included in the study. Results: Patients subjected to percutaneous needle aspiration had a higher success rate of 62.5% then those with conservative treatment. But this was lower than those who were percutaneously drained (100%). Conclusion: Interventional therapy with chemotherapy is more effective than conservative management alone. In interventional therapy, percutaneous drainage is best option for treatment of amoebic liver abscess.