Haematological scoring system: Can it be used as a routine screening tool in early diagnosis of neonatal sepsis?

Abstract

Background: Septicaemia neonatarum is a clinical syndrome characterized by signs and symptoms of infection accompanied by bacteremia in the first month of life. Early diagnosis of neonatal sepsis is essential for early therapy. Objective: To evaluate the role of hematologic scoring system (HSS) in the early diagnosis of neonatal sepsis. Materials & Methods: This is cross sectional study. It includes 185 neonates admitted in NICU, tertiary care centre in Tamilnadu, who were clinically suspected of sepsis. Hematological parameters were measured in all cases and blood culture was done. Results: On statistical evaluation, Total PMN, immature PMN count, and Immature to total neutrophil ratio had good sensitivity. Score ≥ 5 was most reliable indicator of sepsis. Conclusion: HSS is useful screening tool in diagnosing the neonates with sepsis and provides a guideline for appropriate, prompt antibiotic therapy and reducing the mortality.