Solid pseudopapillary neoplasms of the pancreas clinical analysis of 8 cases from North India and review literature

Abstract

Solid pseudopapillary neoplasm (SPN) is rare pancreatic neoplasm. Predominantly in young female, present with abdominal lump and pain. These tumors are indolent in nature. In our case series, 8 cases in 6 years period (2012 to 2018), with one of them is unusual site in retroperitoneum. Mean age of presentation was 25.6 years. Presenting symptom was dull aching pain (80%), lump in upper abdomen (65%). Mean size was 11.6 cm on imaging abdomen. All patients underwent surgery, one patient underwent preoperative FNAC due to unusual location. Mean postoperative hospital stay was 13.9 days with no mortality. By immunohistochemistry, all cases stained positive for vimentin, CD 10 and all were negative for cytokeratin and Ki67