A comparative study to assess relation of platelet count, neutrophil and lymphocyte ration as predictor of pre eclampsia in normotensive and pre-eclamptic women

Abstract

Objectives: To evaluate the relationship between hypertensive disorders in pregnancy and platelet count and neutrophil to lymphocyte ration and to find out their association with severity of pre-eclamptic disorders in pregnancy. Material and Methods: Study done on 100 subjects, 50 normal pregnant women and 50 pregnant women with varying degree of PIH between January 2017 to December 2017 from antenatal clinic and inpatient ward. During third trimester blood samples were taken every four week for estimating hemoglobin, WBC, cretinine, uric acid, platelets count besides routine investigations.Result: Platelet count decreases, neutrophil and lymphocyte ration increases with increment in severity of hypertension. Conclusion: Pre-eclamptic women have decreased platelet count and increased neutrophil to lymphocyte ration as compared to healthy pregnant women. Thus, estimation of platelet count and N:L ration can be considered as an early economical and rapid procedure of assessment of severity of hypertensive disorders in pregnancy cases and their management which can be done even in rural hospitals.