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A case report: Acute neuromyelitis in pregnancy

International Journal of Clinical Obstetrics and Gynaecology · 2017 · Vol. 1(2) · pp. 88–90

Kavitha LB✉(ESI - Post Graduate Institute of Medical Science and Research)Sreelatha S(ESI - Post Graduate Institute of Medical Science and Research)Vandana Ambastha(ESI - Post Graduate Institute of Medical Science and Research)Shruthi K(ESI - Post Graduate Institute of Medical Science and Research)Sumaya SumayaSandeep SherawatVedavathy Nayak(ESI - Post Graduate Institute of Medical Science and Research)

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Abstract

Neuromyelitis optica spectrum disorder (NMOSD) is a demyleinating disease of the central nervous system. NMOSD is characterized by severe relapse of optic neuritis, longitudinal extensive myelitis and the presence of anti aquaporin-4 IgG (AQP4-IgG) in serum. Female factors like genetic, epi-genetic, or hormonal, may play an important role in pathogenesis. Female gonadal hormones, estrogen and progesterone, rise significantly during pregnancy, and decrease during the postpartum period. We are reporting a case of Gravida 2 Para1 Living1 Abortion 0 with full term with known case of acute neuromyelitis (on treatment for 3 years). Patient delivered vaginally, post natal period was uneventful.

Multiple Sclerosis Research StudiesNeuromyelitis opticaMedicinePregnancyOptic neuritisPostpartum periodMultiple sclerosisAquaporin 4MyelitisCentral nervous systemHormone

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References

The clinical course of neuromyelitis optica (Devic’s syndrome)

Neurology · 1999 · 1,805 citations

Revised diagnostic criteria for neuromyelitis optica