articleTop 1% cited
X-rays can trigger the FLASH effect: Ultra-high dose-rate synchrotron light source prevents normal brain injury after whole brain irradiation in mice
Radiotherapy and Oncology · 2018 · Vol. 129(3) · pp. 582–588
Pierre Montay‐Gruel(University of Lausanne)Audrey Bouchet(Université Grenoble Alpes)Maud Jaccard(University of Lausanne)David Patin(Institute of Radiation Physics)Raphaël Serduc✉(Université Grenoble Alpes)Warren Aim(Université Grenoble Alpes)Kristoffer Petersson(University of Lausanne)Benoît Petit(University of Lausanne)Claude Bailat(University of Lausanne)Jean Bourhis(University of Lausanne)Elke Bräuer‐Krisch(European Synchrotron Radiation Facility)Marie‐Catherine Vozenin✉(University of Lausanne)
Radiation Therapy and DosimetryGlioma Diagnosis and TreatmentEffects of Radiation ExposureAstrogliosisIrradiationHippocampal formationFlash (photography)SynchrotronDose rateNuclear medicineMedicinePhysicsOptics
MeSH terms
AnimalsBrain InjuriesFemaleHippocampusMemoryMice, Inbred C57BLRadiation Injuries, ExperimentalX-RaysCranial IrradiationSynchrotronsMice
Funding
- Biltema Foundation
- Agence Nationale de la Recherche
- French Norwegian Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Ligue Contre le Cancer
- Ministère de l'Enseignement Supérieur et de la Recherche
- Fondation ISREC
- Société d'Accélération du Transfert de Technologies
Citations
391
FWCI
24.01
field-weighted impact
References
40
Percentile
100%
vs. same field & year
Citations per year
Cited by
Ultra-High Dose Rate (FLASH) Radiotherapy: Silver Bullet or Fool's Gold?
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Treatment of a first patient with FLASH-radiotherapy
Radiotherapy and Oncology · 2019 · 909 citations
Clinical translation of FLASH radiotherapy: Why and how?
Radiotherapy and Oncology · 2019 · 451 citations
References
Ultrahigh dose-rate FLASH irradiation increases the differential response between normal and tumor tissue in mice
Science Translational Medicine · 2014 · 1,362 citations
Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma
New England Journal of Medicine · 2005 · 21,276 citations
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
The Lancet Oncology · 2009 · 7,709 citations
Irradiation in a flash: Unique sparing of memory in mice after whole brain irradiation with dose rates above 100 Gy/s
Radiotherapy and Oncology · 2017 · 652 citations
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