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SGLT2 inhibitors and mechanisms of cardiovascular benefit: a state-of-the-art review

Diabetologia · 2018 · Vol. 61(10) · pp. 2108–2117
Subodh VermaJohn J.V. McMurray
Diabetes Treatment and ManagementPancreatic function and diabetesHeart Failure Treatment and ManagementEmpagliflozinNatriuresisAfterloadHeart failureMedicineAdipokineContext (archaeology)DiuresisDiabetes mellitusPharmacology

MeSH terms

Sodium-Glucose Transporter 2 InhibitorsAnimalsBenzhydryl CompoundsBlood GlucoseCardiovascular DiseasesDiabetes Mellitus, Type 2GlucosidesHeartHeart VentriclesHumansHypoglycemic AgentsKidneyDiabetes ComplicationsAdipokines

Funding

  • Amgen
  • Bristol-Myers Squibb
  • Eli Lilly and Company
  • Pfizer
  • AstraZeneca
  • GlaxoSmithKline
  • Sanofi
  • Valeant Pharmaceuticals International
  • University of Glasgow
  • Novo Nordisk
Citations
925
FWCI
66.35
field-weighted impact
References
67
Percentile
100%
vs. same field & year
Citations per year
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References
Myocardial Fatty Acid Metabolism in Health and Disease
Physiological Reviews · 2010 · 2,111 citations
Adipokines: molecular links between obesity and atheroslcerosis
American Journal of Physiology-Heart and Circulatory Physiology · 2005 · 935 citations
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
New England Journal of Medicine · 2015 · 11,756 citations
Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes
New England Journal of Medicine · 2017 · 7,624 citations
Diabetic Cardiomyopathy
Circulation Research · 2018 · 1,717 citations
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