Selected Schiff base coordination complexes and their microbial application: A review

Abstract

Today coordination chemistry comprises a large body of inorganic chemistry research. It is mainly the chemistry of metal complexes has fascinated and inspired the chemists all over the world. There is an ever increasing academic, commercial and biochemical interest on the metal complexes of organic chelating ligands. This has resulted in the emergence of allied fields like organometallic chemistry, homogenous catalysis and bioinorganic chemistry. Among the chelating ligands, Schiff bases have attracted the attention of chemists due to the case of preparation and complexation. In this review we have focused on the synthesis of some selected Schiff base coordination complexes and their biological application such as antibacterial, antifungal, anticancer, DNA interaction, cytotoxicity, Analgesic and anti-inflammatory, Antianxiety activities, ribonucleotide reductage, Anti-HIV activity.