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Inhibition of PI3K/Akt/mTOR pathway by apigenin induces apoptosis and autophagy in hepatocellular carcinoma cells

Biomedicine & Pharmacotherapy · 2018 · Vol. 103 · pp. 699–707
Jiali YangCuicui PiGuanghui Wang
Autophagy in Disease and TherapyFlavonoids in Medical ResearchBioactive Natural Diterpenoids ResearchApigeninAutophagyPI3K/AKT/mTOR pathwayApoptosisProtein kinase BProgrammed cell deathChemistryCell growthCancer researchSignal transduction

MeSH terms

Phosphoinositide-3 Kinase InhibitorsAnimalsAntineoplastic AgentsAutophagyCarcinoma, HepatocellularHumansLiver NeoplasmsMaleMice, Inbred BALB CMice, NudeApoptosisPhosphatidylinositol 3-KinasesXenograft Model Antitumor AssaysApigeninCell Proliferation
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427
FWCI
22.04
field-weighted impact
References
49
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