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Frailty and Multimorbidity: A Systematic Review and Meta-analysis
The Journals of Gerontology Series A · 2018 · Vol. 74(5) · pp. 659–666
Davide Liborio Vetrano✉(Karolinska Institutet)Katie Palmer(IRCCS San Camillo Hospital)Alessandra Marengoni(University of Brescia)Emanuele Marzetti(Università Cattolica del Sacro Cuore)Fabrizia LattanzioRegina Roller‐Wirnsberger(Medical University of Graz)Luz López SamaniegoLeocadio Rodríguez‐Mañas(Hospital Universitario de Getafe)Roberto Bernabei(Università Cattolica del Sacro Cuore)Graziano Onder(Università Cattolica del Sacro Cuore)Joint Action ADVANTAGE WP4 Group
Abstract
Frailty and multimorbidity are two related conditions in older adults. Most frail individuals are also multimorbid, but fewer multimorbid ones also present frailty. Our findings are not conclusive regarding the causal association between the two conditions. Further longitudinal and well-designed studies may help to untangle the relationship between frailty and multimorbidity.
Frailty in Older AdultsChronic Disease Management StrategiesHealth Systems, Economic Evaluations, Quality of LifeConfidence intervalMedicineMeta-analysisOdds ratioMultimorbidityDemographyMEDLINEGerontologyComorbidityInternal medicine
MeSH terms
FrailtyMultimorbidityAgedHumansRisk Factors
Funding
- European Commission
- Medizinischen Hochschule Hannover
Citations
753
FWCI
27.29
field-weighted impact
References
74
Percentile
100%
vs. same field & year
Citations per year
References
Untangling the Concepts of Disability, Frailty, and Comorbidity: Implications for Improved Targeting and Care
The Journals of Gerontology Series A · 2004 · 4,018 citations
Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study
The Lancet · 2012 · 6,910 citations
Frailty in Relation to the Accumulation of Deficits
The Journals of Gerontology Series A · 2007 · 2,868 citations
Frailty in elderly people
The Lancet · 2013 · 9,027 citations
Frailty in Older Adults: Evidence for a Phenotype
The Journals of Gerontology Series A · 2001 · 23,899 citations
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