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Meta-analysis comparing upfront surgery with neoadjuvant treatment in patients with resectable or borderline resectable pancreatic cancer
British journal of surgery · 2018 · Vol. 105(8) · pp. 946–958
Eva Versteijne✉Jantien A. Vogel(Amsterdam UMC Location University of Amsterdam)Marc G. Besselink(Amsterdam UMC Location University of Amsterdam)Olivier R. Busch(Amsterdam UMC Location University of Amsterdam)Johanna W. Wilmink(Amsterdam UMC Location University of Amsterdam)Joost G. Daams(Amsterdam UMC Location University of Amsterdam)Casper H.J. van Eijck(Erasmus University Rotterdam)Bas Groot Koerkamp(Erasmus University Rotterdam)C. RaschGeertjan van Tienhoven
Abstract
Neoadjuvant treatment appears to improve overall survival by intention to treat, despite lower overall resection rates for resectable or borderline resectable pancreatic cancer. PROSPERO registration number: CRD42016049374.
Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and TreatmentNeuroendocrine Tumor Research AdvancesMedicineNeoadjuvant therapyPancreatic cancerLymph nodeCochrane LibrarySurgeryMeta-analysisPathologicalSurvival rateOncology
MeSH terms
AgedHumansMiddle AgedPancreatectomyPancreatic NeoplasmsTime FactorsSurvival RateTreatment OutcomeNeoadjuvant TherapyIntention to Treat Analysis
Funding
- KWF Kankerbestrijding
Citations
510
FWCI
22.18
field-weighted impact
References
70
Percentile
100%
vs. same field & year
Citations per year
Cited by
Upfront surgery in borderline resectable pancreatic cancer
International Journal of Surgery Science · 2019 · 0 citations
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World Journal of Gastroenterology · 2018 · 1,935 citations
References
Preoperative/Neoadjuvant Therapy in Pancreatic Cancer: A Systematic Review and Meta-analysis of Response and Resection Percentages
PLoS Medicine · 2010 · 1,566 citations
Borderline Resectable Pancreatic Cancer: Need for Standardization and Methods for Optimal Clinical Trial Design
Annals of Surgical Oncology · 2013 · 337 citations
The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
BMJ · 2011 · 33,606 citations
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration
BMJ · 2009 · 17,433 citations
The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
PLoS Medicine · 2009 · 27,702 citations
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