Synthesis, spectral analysis, X-ray structure characterization and biological evaluation of N, N'-bis (p-nitrophenylmethylene) Hexane 1,6-diamine as potential antioxidant Schiff base compound

Abstract

The title compound have been synthesized and characterized by routine MS, IR and NMR spectrometry methods. Single crystal X-ray diffraction analysis showed that N,N'-bis(4-nitrophenylmethylene)hexane-1,6-diamine compound crystallized in monoclinic P21/c space group with a = 6,1569(7)A, b = 5,0751(5)A, c = 30,631(4) A, β = 94,509(7)° and z = 2. Crystal data were collected using Enraf-Nonius CAD4 X-ray diffractometer with monochromatic Kα radiation of Cu (λ = 1.54187A). The structure was solved by direct methods and refined on F2 by full-matrix least-squares procedures to the final R1 of 0,152, using SHELXL programs. Crystalline network cohesion of this compound was essentially assured by C-H…O hydrogen bounds and dipole-dipole type interactions. Biological investigation carried out according DPPH and ABTS methods, revealed that this compound had antioxidant activity.