Melorheostosis: Case report of rare disease

Abstract

Introduction: Melorheostosis is a rare chronic bone disease, characterized by linear hyperostosis along the bone cortex. First case described in 1922 by Leri and Joanny. It can affect any bone, being more frequent in long bones. The etiology remains unknown although several theories have been proposed. Men and women are equally affected, and no hereditary features have been discovered. Onset is insidious, and mostjj common symptoms are pain, deformity and joint stiffness. The diagnosis is obtained by combining the clinical and radiological findings (mainly radiography with typical image in