Metabolomic profiling of ethanolic extracts of the fruit of Xylopia aethiopica (Dunal) a. rich using gas chromatography and high-performance liquid chromatography techniques

Abstract

The study was aimed at identifying the phytochemicals present in the ethanolic extracts of the dried fruit of Xylopia aethiopica by GC-MS and HPLC-DAD analyses. A total of 39, 38 and 35 compounds were identified in the ethanol extract (EE), residual fraction (RF) and n-hexane fraction (HF) of ethanolic extracts of X. aethiopica, respectively by the GC-MS. The HPLC-DAD analysis revealed the presence ofxylopic acid, chlorogenic acid, caffeic acid and ellagic acid in all the samples while apigenin, kaempferol, rutin and quercetin were only present in EE and RF. The results postulated that the ethanolic extracts and the fractions of the extract contain various bioactive compounds which can be used for the treatment and management of various diseases.