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Yeast surface display platform for rapid discovery of conformationally selective nanobodies

Nature Structural & Molecular Biology · 2018 · Vol. 25(3) · pp. 289–296
Conor McMahonAlexander S. BaierRoberta PascoluttiMarcin WegreckiSanduo ZhengJanice X. OngSarah C. ErlandsonDaniel HilgerSøren G. F. RasmussenAaron M. RingAashish ManglikAndrew C. Kruse
Monoclonal and Polyclonal Antibodies ResearchBiochemical and Structural CharacterizationGlycosylation and Glycoproteins ResearchYeastChemistryComputational biologyDrug discoveryNanotechnologyBiologyCell biologyBiochemistryMaterials science

MeSH terms

Antibody SpecificityAntigensCell SeparationFlow CytometryHumansProtein ConformationYeastsReceptors, G-Protein-CoupledCell Surface Display TechniquesSingle-Domain Antibodies

Funding

  • Richard and Susan Smith Family Foundation
  • Vallee Foundation
  • Lundbeckfonden
  • H. Lundbeck A/S
  • National Institutes of Health
Citations
570
FWCI
35.37
field-weighted impact
References
40
Percentile
100%
vs. same field & year
Citations per year
References
Nanobodies: Natural Single-Domain Antibodies
Annual Review of Biochemistry · 2013 · 2,223 citations
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Yeast surface display platform for rapid discovery of conformationally selective nanobodies · Scinovex