review Open AccessTop 1% cited
G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?
Molecular Pharmacology · 2018 · Vol. 93(4) · pp. 251–258
Krishna Sriram✉(University of California, San Diego)Paul A. Insel(University of California, San Diego)
Receptor Mechanisms and SignalingComputational Drug Discovery MethodsPharmacogenetics and Drug MetabolismG protein-coupled receptorDrugBankchEMBLDrug discoveryComputational biologyBiologyPharmacologyDrugBioinformaticsReceptor
MeSH terms
AnimalsPharmaceutical PreparationsHumansDatabases, FactualDrug Delivery SystemsReceptors, G-Protein-Coupled
Funding
- U.S. Department of Defense
- Bristol-Myers Squibb
- American Society for Pharmacology and Experimental Therapeutics
- National Institutes of Health
Citations
1,263
FWCI
42.04
field-weighted impact
References
35
Percentile
100%
vs. same field & year
Citations per year
References
UniProt: the Universal Protein knowledgebase
Nucleic Acids Research · 2003 · 7,806 citations
Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI Inhibitors
Cancers · 2016 · 590 citations
A comprehensive map of molecular drug targets
Nature Reviews Drug Discovery · 2016 · 2,383 citations
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