Correlation between glycosylated hemoglobin level and lipid profile in patients with Diabetes mellitus

Abstract

The present study was conducted in the Department of Biochemistry, M.N.R. Medical College, Sangareddy District, Telangana, State, India. A total of n=75 subjects were selected, comprising n=50 subjects (n=25 male and n=25 female) with known Diabetes mellitus and n=25 non-diabetic healthy controls. The study was aimed to investigate the pattern of dyslipidemia among the subjects and understand its association with glycosylated hemoglobin (HbA1c) level in diabetic and healthy controls. Biochemical parameters were estimated by following standard methods. The mean and SD values of fasting blood glucose (164.56 ± 10.41) and post prandial blood glucose (228.60 ± 12.66) were significantly (p8 was seen in n=34 (68%) of diabetic patients. Poor glycemic control was associated with dyslipidemia in n=24 (48%) diabetic patients. Whereas, 6 cases (12%) showed worse glycemic control with HbA1c level > 9%, and 8 cases showed good glycemic control with HbA1C level ≤ 6%. The mean±SD of serum total cholesterol (216.48 ± 10.87), triglycerides (214.84 ± 8.98), LDL-cholesterol (149.52 ± 5.06) were significantly (p