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Contact killing and antimicrobial properties of copper

Journal of Applied Microbiology · 2017 · Vol. 124(5) · pp. 1032–1046
Marin VincentRaphaël E. DuvalPhilippe HartemannMarc Engels‐Deutsch

Abstract

With the emergence of antibiotic resistance, the interest for antimicrobial agents has recently increased again in public health. Copper was recognized in 2008 by the United States Environmental Protection Agency (EPA) as the first metallic antimicrobial agent. This led to many investigations of the various properties of copper as an antibacterial, antifungal and antiviral agent. This review summarizes the latest findings about 'contact killing', the mechanism of action of copper nanoparticles and the different ways micro-organisms develop resistance to copper.

Nanoparticles: synthesis and applicationsBacterial biofilms and quorum sensingHealthcare and Environmental Waste ManagementAntimicrobialCopperAnti-Infective AgentsAntibiotic resistanceAntifungalMicrobiologyAntibacterial agentDrug resistanceAntibioticsBiology

MeSH terms

Anti-Infective AgentsAnti-Bacterial AgentsAntifungal AgentsAntiviral AgentsCopperDrug Resistance, Microbial

Funding

  • U.S. Environmental Protection Agency
  • Centre National de la Recherche Scientifique
Citations
658
FWCI
12.54
field-weighted impact
References
162
Percentile
99%
vs. same field & year
Citations per year
References
Copper: An essential metal in biology
Current Biology · 2011 · 1,148 citations
Metallic Copper as an Antimicrobial Surface
Applied and Environmental Microbiology · 2010 · 1,580 citations
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