article Open AccessTop 1% cited
Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis
JNCI Journal of the National Cancer Institute · 2017 · Vol. 110(3) · pp. 304–315
Yibing Yang(The First Affiliated Hospital, Sun Yat-sen University)Xinya Gao(Key Laboratory of Guangdong Province)Maolei Zhang(Key Laboratory of Guangdong Province)Sheng Yan(Key Laboratory of Guangdong Province)Chengjun Sun(Key Laboratory of Guangdong Province)Feizhe Xiao(Sun Yat-sen University)Nunu Huang(Sun Yat-sen University)Xuesong Yang(The First Affiliated Hospital, Sun Yat-sen University)Kun Zhao(The First Affiliated Hospital, Sun Yat-sen University)Huangkai Zhou(Sun Yat-sen University)Suyun Huang(The University of Texas MD Anderson Cancer Center)Bo Xie(Sun Yat-sen University)Nu Zhang✉(Sun Yat-sen University)
Abstract
Endogenous circRNA encodes a functional protein in human cells, and circ-FBXW7 and FBXW7-185aa have potential prognostic implications in brain cancer.
Circular RNAs in diseasesMicroRNA in disease regulationCancer-related molecular mechanisms researchCarcinogenesisCircular RNAGliomaCancer researchRNABiologyCell biologyGeneticsCancerGene
MeSH terms
F-Box-WD Repeat-Containing Protein 7RNA, CircularAnimalsBrainBrain NeoplasmsCell CycleCell Transformation, NeoplasticFemaleGlioblastomaHalf-LifeHumansMice, Inbred BALB CMice, NudeNeoplasm TransplantationRNA
Funding
- National Natural Science Foundation of China
- National Cancer Institute
Citations
1,202
FWCI
46.79
field-weighted impact
References
45
Percentile
100%
vs. same field & year
Citations per year
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References
Exon-intron circular RNAs regulate transcription in the nucleus
Nature Structural & Molecular Biology · 2015 · 3,018 citations
Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed
Molecular Cell · 2015 · 2,603 citations
Detecting and characterizing circular RNAs
Nature Biotechnology · 2014 · 2,893 citations
Exon Circularization Requires Canonical Splice Signals
Cell Reports · 2014 · 791 citations
Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types
PLoS ONE · 2012 · 2,577 citations
Circular Intronic Long Noncoding RNAs
Molecular Cell · 2013 · 2,227 citations
Circular RNAs are a large class of animal RNAs with regulatory potency
Nature · 2013 · 8,404 citations
Natural RNA circles function as efficient microRNA sponges
Nature · 2013 · 8,387 citations
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