Hepatoprotective activity of husk extract and fractions of Zea mays against alloxan-induced oxidative stress in diabetic Rats

Abstract

Zea mays L. (Poacae), an annual grass, traditionally used to treat various diseases was evaluated for antioxidative stress and hepatoprotective potentials against alloxan-induced injuries in diabetic rats. Antioxidative stress and hepatoprotective activities of husk extract and fractions (187-748 mg/kg) were assessed by determining oxidative stress markers levels, liver tests and histopathology of liver. The husk extract and fractions caused significant (p