Efficacy of Unani formulation and Roghan-e-Dhatura in Adhesive Capsulitis: An open labeled interventional study

Abstract

Background and Objectives: Adhesive Capsulitis (AC) is commonly known as Frozen Shoulder Syndrome (FSS) is a condition characterized by intense shoulder pain, gradual fibrosis of the glenohumeral joint that causes a limited range of motion, and contracture of the glenohumeral joint capsule. The disease peaks between 40 and 70 years of age and 10 to 36% of the individuals with Diabetes mellitus are mostly affected followed by Hypothyroidism and Hyperthyroidism. In conventional medicine it is being treated with pharmacologically, non-pharmacologically and with surgery. In Unani system of medicine AC is considered as a type of articular disease and treated according to the principles of Amraz-e-Mafasil with drugs and regimens. In this study a Unani formulation and Roghan-e- Dahtura is selected to validate its indication as effective in painful joints.Methods: This study was conducted as an open labeled interventional without control pre and post analysis on 30 patients with oral Unani formulation (Sibr, Halela Zard, Suranjan Sheerin, Saqmooniya and Aabe Mako) and local application of Roghan-e-Dhatura for 28 days with follow ups on, 7th, 14th, 21th and 28th day. The pre and post treatment effects were assessed objectively with VAS, SPADI. Results: The study outcome measured with mean and standard deviation in VAS, before treatment 8.33±0.55 and after treatment 2.23±0.73, with p value < 0.001 and SPADI 76.51±2.80 and 16.61±6.87, found statistically highly significant with p value