Exposure to uppercott pesticide induces reproductive toxicity in male and female rats

Abstract

In this study, the effect of Uppercott was investigated in parents and first generation offspring of albino Wistar rats. The rats were distributed into ten groups of nine (9) rats each, five groups each for male and female rats respectively. Groups 1 & 2 were taken as normal and oil control respectively for both male and female rats, groups three (3) to five (5) were given 2.5%, 5% and 7.5% of LD50 Uppercott value for 28 days. The rats were then mated in the ratio of 2:3 (2 male rats to 3 female rats) until pregnancy was established. Result indicated that Uppercott exposure produced a significant (p