Evaluation of In vitro anticancer activity of Tarenna asiatica (L.) fruits ethanolic extract against human breast cancer

Abstract

Tarenna asiatica (L.) is a medicinal plant from Kolli hills, Eastern Ghats, India. Fruit the Tarenna asiatica is an edible one and it has been used traditionally for treatment of a number of diseases. In the present study the ethanol extract of the edible fruit of the plant have been tested for anticancer activity. The extract was prepared by soxhlet separation and vacuum evaporator method. The in-vitro anticancer studies were performed against human breast cancer cell line and Eagles Minimum Essential Medium containing 10% fetal bovine serum (FBS) was used to analyze the cell growth inhibition. The results showed that the ethanol extract of wild edible fruit Tarenna asiatica (L.) possessed a high amount of anticancer activity and the IC50 value also high as 237.08 µg/ml. The plant investigated possesses remarkable anticancer activity and hence isolation of the compound contributing to the activity may lead to develop at a novel and natural phytomedicine for the disease.