article
Detecting the presence of antitumor terpenoids in bark of white birch from North-eastern Bulgaria
Journal of Pharmacognosy and Phytochemistry · 2017 · Vol. 6(2) · pp. 164–167
Abstract
For the first time a chemical analysis of white birch Betula pendula Roth. bark samples from North-eastern Bulgaria region was carried out in order to demonstrate the presence of pentacyclic triterpenoids of ursane, lupane, and oleanane families. A liquid-phase extraction procedure was adapted. The results both from TLS and GC-MS analysis confirmed the presence of two compounds of interest: betulin and I±-amyrin in ratio close to 7:1. Detectable quantity of betulinic acid in the samples was not found.
Natural product bioactivities and synthesisPlant biochemistry and biosynthesisBetulinBetulinic acidOleananeBark (sound)TerpenoidTriterpenoidBetula pendulaChemistryTriterpeneExtraction (chemistry)
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