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Analysis of bioactive compounds in methanol extract of Aplotaxis auriculata rhizome using GC-MS

Journal of Pharmacognosy and Phytochemistry · 2017 · Vol. 6(3) · pp. 243–247

Abstract

The objective of this study was to determine the bioactive compounds from the methanolic extract of Aplotaxis auriculata rhizome and evaluate its biological activity by GC-MS analysis. The chemical constituents in this methanolic extract were subjected to the Perkin-Elmer Gas Chromatography - Mass Spectrometric analysis. Fifteen bioactive chemical compounds have been identified in the plant extract. This identification was based on the peak area, retention time, molecular weight and molecular formula. In this investigation the compounds like Cyclohexane, 1-Ethenyl – 1 – Methyl - 2, 4 – bis (1 – Methylethenyl ) - 2, 4 - diisopropenyl -1- Methyl - 1 - Vinylcyclohexane, 5 – Oxatricyclo - [8.2.0.0 (4,6) ] -Dodecane, KW3 Aus Epiglobulol, Bicyclo [5.3.0] nonane, 1,4 – Dimethyl - 3 - (2 - Methyl – 1- Propenyl 1- Cycloheptene, 10,12- Hexa decadien -1- ol, 9,12,15 - Octadecatrienoic acid, Androstan-17- one, 3 – ethyl - 3- hydroxyl - (5I±) - 3- Ethyl - 3 - hydroxyandrostan - 17- one, n - Hexadecanoic acid, Doconexent cis - 4, 7, 10, 13, 16, 19 - Docosahexanoic acid and Azuleno [4,5 b] furan – 2 (3H) – one were predominantly found in the Aplotaxis auriculata rhizome extract.

Computational Drug Discovery MethodsDiverse Scientific Research StudiesPhytochemicals and Medicinal PlantsRhizomeChemistryGas chromatographyFriedelinEthyl acetatePentadecaneMethanolGas chromatography–mass spectrometryPentadecanoic acidOrganic chemistry
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