Evaluation of in vitro Antiurolithiatic Activity of Vaishvanara Churna

Abstract

Vaishvanara churna is a ayurvedic formulation used traditionally as laxative, analgesic, anti-inflammatory agent.rnVaishvanara churna composed of Saindhava lavana, Ajowan, Ajamoda, Shunti, and Haritaki. Effect of aqueousrnextract of churna on calcium oxalate crystallization was evaluated. Calcium oxalate crystallization was induced byrnthe addition of 0.01M sodium oxalate solutions in synthetic urine. The effect of extract (100 and 200 μg/ml) wasrnstudied by time course measurement of absorbance at 620 nm for ten minutes by means of a spectrophotometer.rnAqueous extract at 100 and 200 μg/ml concentration of extract showed inhibition at 120 sec (17.85 and 25 %), andrnmaximum inhibition of the crystallization of calcium oxalate at 600 seconds (50 and 53.51 %).