Anti protein denaturation activity and bioactive compound screening of Piper betel aqueous and alcoholic leaf extract

Abstract

Nature provides several herbal phyto-chemicals for the beneficial of human since the ancient periods. Piper betel is one of the common and valuable herbs in traditional medicine. In the current study, qualitative screening of different bioactive compounds and Anti protein de-naturation property was checked in aqueous and alcoholic extract of Piper betel. Three different concentration 50, 75, 100 microgram/ml was taken for protein de-naturation method using same amount sodium diclofenec as a reference drug. The study revealed that P. bete have several bioactive compounds and significant Anti protein de-naturation property. Presence of several phyto-chemicals may help to scavenge the highly heterogeneous conformational isomers derived by denatured proteins in human. So, in future it could be possible to develop a new phyto derived drug for membrane destabilization related disease in human.