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Photometric method for estimation of Magaldrate
The Pharma Innovation · 2015 · Vol. 4(6b) · pp. 60–63
Krishnasis Chakraborty✉(Al-Ameen College of Pharmacy)G MubeenRitu Kimbahune(Al-Ameen College of Pharmacy)N Lalitha(Al-Ameen College of Pharmacy)Yajnesh Pai(Al-Ameen College of Pharmacy)
Abstract
The complex formation between Magaldrate, Magnesium and Aluminium hydroxide salt, and Eriochrome Black T at pH10 has been proposed for photometric estimation of Magaldrate. The absorbance of stable violet colored complex of Eriochrome Black T and Magnesium and Aluminium ions of Magaldrate was measured at 527 nm and used for quantitation by single point method. The method has been successfully employed for Magaldrate tablets and the obtained results were found complying with official specification. The method has been validated as per ICH guidelines and the results for all the parameters were found in the recommended limits.
Analytical Methods in PharmaceuticalsAnalytical Chemistry and ChromatographyAnalytical Chemistry and SensorsEriochrome Black TAbsorbanceMagnesiumAluminiumSalt (chemistry)Aluminium hydroxideChemistryMaterials scienceNuclear chemistryChromatography
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