Evaluation of aqueous and methanolic extract of leaves of Epipremnum aureum for radical scavenging activity by DPPH Method, total phenolic content, reducing capacity assay and FRAP assay

Abstract

Objective: Evaluation of aqueous and methanolic extracts of Epipremnum aureum leaves for antioxidant, total phenolic contents, total reduction capacity and FRAP assay.Materials and Methods: The Antioxidant evaluation of the aqueous and methanolic extracts of Epipremnum aureum leaves were carried out by using DPPH radical scavenging activity assay, total reduction capacity assay and FRAP assay.Results: The results of the DPPH radical scavenging activity indicate a concentration dependent antioxidant activity of Epipremnum aureum is comparable with standard ascorbic acid and IC50 was found to be 100 µg/ml. The total phenolic content was determined and found to be 852.379 mg/ml GAE for aqueous extract and 559.522 mg/ml GAE. The FRAP values of aqueous and methanolic extracts were found to be 1.932 and 1.716 respectively which are comparable to standard ascorbic acid.  Conclusion: Our findings provide evidence that the crude methanolic and aqueous extract of Epipremnum aureum is a potential source of natural antioxidants, and this justified its uses in folkloric medicines.