Susceptibility status of Dengue vector (Aedes aegypti) against different insecticides in district Mansehra, Khyber Pakhtunkhwa, Pakistan

Abstract

Aedes aegypti is the primary and Aedes albopictus is the secondary vector of dengue virus and is of Public health concern. The primary strategy to control the spread of dengue is to control the disease vector density which mainly depends upon the use of chemical insecticides but unfortunately the control intervention facing operational challenges regarding insecticides resistance in dengue vector and other vector borne diseases. But no data was available on susceptibility of dengue vector of Mansehra. The aim of this study was to assess the susceptibility level of Aedes aegypti to different insecticides recommended by World Health Organization. During this study Aedes aegypti larvae were collected from five localities of district Mansehra and after rearing in the insectary the resistance/susceptibility status of F1 generation was determined by using World Health Organization (WHO) test kit, utilizing papers impregnated with DDT 4%, Malathion 5%, Bendiocarb 0.1%, Lambdacialotrina 0.05% and Deltamethrin 0.05%. The test results showed that the Aedes aegypti population of district Mansehra is resistant to DDT, Malathion, Lambdacialotrina and Deltamethrin but Bendiocarb is placed under the verification required status. The results of this study concludes that if appropriate resistance management strategies are applied in this area then the high level of resistance can be prevent or delayed. This study provides important evidence base data for strategic planning for vector control in district Mansehra.