Clinicopathological and imaging variants of Ameloblastoma - Case series

Abstract

Ameloblastoma is the second most common intraosseous benign odontogenic tumor usually affecting the posterior region of mandible. This tumor exhibits a locally aggressive behavior. It is seen in the third to fifth decades of life. In the recent histological classification of odontogenic tumors from the World Health Organization (WHO), Ameloblastoma is defined as a benign, locally invasive epithelial odontogenic neoplasm of putative enamel organ origin. Radiographically the lesion is variable in appearance and may be unilocular or multilocular, with well-defined cortical borders in the mandible and ill-defined margins in the maxilla. A number of morphological variants of Ameloblastoma have been documented in the literature and at times, may pose a diagnostic challenge to the pathologist. Recognition of the subtypes of Ameloblastoma is important, as it has been documented that some subtypes may exhibit a more aggressive biological behavior than the so-called “conventional” Ameloblastomas.