Effect of induced lead intoxication on serological parameters without or with different antioxidants in broiler chicken

Abstract

In the present study effect of lead intoxication on serum biochemical of broiler chicken has been done. The birds were divided into six groups viz. A, B, C, D, E and F. Group-A served as control whereas group-B received lead acetate @ 200 mg/kg basal diet for 42 days simultaneously Ascorbic acid @ 200 mg/kg basal diet, Vitamin-E @ 100/mg/kg and Se @ 0.1 mg/kg basal diet, DL-methionine @ 100 mg/ kg and methanolic extract of Cissus quadrangularis (CQE) @ 400 mg/kg basal diet were given to group B, C, D, E and F respectively. The biochemical profile of treated with various levels of antioxidants on day 21 and 42 were reported total protein (6.05±0.47 to 6.85±0.39 and3.83±0.09 to 4.60±0.29 ), albumin (2.77±0.09 to 3.77±0.24 and 2.25±0.09 to 2.95±0.16 ), albumin: globulin ratio (0.74±0.04 to 1.89±0.49 and1.08±0.13 to 2.06±0.25 ), Serum glutamic oxaloacetic transaminase (1.26±0.16 to 2.62±0.13 and 0.96±0.16 to1.72±0.19 ), Serum glutamic pyruate transaminase (14.07±1.08 to 17.28±0.90 and 8.88±0.25 to14.87±0.49 ), blood urea nitrogen (6.07±0.75 to 11.22±0.45 and 2.98±0.21 to 4.60±0.17), creatinine (0.64±0.05 to 1.50±0.09 and 1.56±0.19 to 2.20±0.15 ) and alkaline phosphatase (3.41±0.25 to 4.40±0.32 and 2.50±0.57 to 4.00±0.78 ). All biochemicals parameters in lead treated group were significantly different (P