Anti-Inflammatory activity of ethanol extract of Hugonia mystax Leaves

Abstract

In the present study anti-inflammatory activity of ethanol extract of leaf of Hugonia mystax were investigated. Preliminary phyto chemical analysis of ethanol extract of Hugonia mystax showed the presence of carbohydrates, flavonoids, steroids, tannins, saponins, terpenoids and absence of alkaloids, proteins, amino acids. The anti-inflammatory activities of ethanol extract leaf of Hugonia mystax were evaluated by carrageenan induced paw edema to determine it’s on chronic phase of inflammation model in rats. Maximum inhibition was obtained at the dose of 200mg/kg of Hugonia mystax leaf after 4 hours of drug treatment in carrageenan induced paw edema. Indomethacine used as a standard drug. The present study suggests that Hugonia mystax leaf possess significant anti-inflammatory activity.