Effect Of Ethanolic Leaf Extract of Kalanchoe Pinnata On Serum Creatine Kinase In Albino Rats

Abstract

The effect of ethanolic extract of fresh leaves of Kalanchoe pinnata on the level of cretatine kinase was investigated using albino rats. The extract with ethanol yielded 7.80%. The albino rats were treated with doses of 200mg/kg and 400mg/kg body weight of the extrat for seven days. Results showed that there was a slight decrease in physical activities and body weight of all the animals treated with the ethanolic extract compared to the control. There was a significant (P > 0.05) increase in serum creatine kinase activity in albino rats treated with the ethanolic extract than the control. Within the groups treated with the ethanolic extract, Group A (400mg/kg body weight) was significantly (P > 0.05) higher than Group B (200mg/kg body weight). This increase value of creatine kinase activity could encourage the supply of energy needed for muscular contraction.