The effect of quinalphos on histopathological changes in the Kidney of fresh water fish, Anabas testudineus

Abstract

The present study investigates histology of kidney of fresh water fish, Anabas testudineus on exposed to 0.5 ppm of quinalphos pesticide. Quinalphos for short term duration (24, 48, 72 and 96 hours) lead to the formation of histopathological lesions of varying intensities on the kidney tissues. Quinalphos is one of the organophosphate insecticides represent one of the most widely used classes of pesticide with high potential for human exposure in both rural and residential environments. The fresh water fish, Anabas testudineus was selected as the test species. 1/10th of 96 hrs LC50 was taken as sublethal concentration of Quinalphos pesticide. After the stipulated period of exposure (24, 48, 72 and 96 hrs) fishes were sacrificed and kidney tissue was isolated and analysed histological changes. Histology of kidney showed pyknosis, vacuolization, nuclear hypertrophy, vacuole formation and defect in renal tubule. The study described the histological structures of kidney of Anabas testudineus during short term exposure period of quinalphos showed occlusion of tubular lumen, cloudy swelling, edema and disorganization of glomerulus were seen in the fish on exposed to quinalphos for short term period.