Analgesic activity of Cryptocarya stocksii plant by hot plate method

Abstract

The Cryptocarya stocksii belongs to the Lauraceae family is an endangered evergreen tree located in Western Ghats of Karnataka, India. Many species of this genus have been used extensively as traditional medicines to cure number of diseases. The present study was conducted to investigate the analgesic activity of petroleum ether, chloroform and ethanol extracts of C. stocksii in an animal model at the dose of 500mg/kg body weight. The analgesic activity of C.S extracts was evaluated by hot plate method. The chloroform extract showed significant analgesic activity of 71.2% and ethanolic extract showed 35.8% followed by petroleum ether of 33.55%, when compared to the standard aspirin at the dose of 150mg/kg body weight.