Management of obesity in polycystic ovary syndrome induced albino rats with Pergularia daemia

Abstract

Obesity plays a major role on both pathophysiology and manifestation of Polycystic syndrome (PCOS). PCOS is a common disorder with various signs and symptoms related to reproductive changes in female. In the present study PCOS was induced in the female rats Rattus norvegicus by injecting Testosterone Propionate. The results indicated an increase in the level of Low density lipoprotein in the serum sample which will lead to obesity. Such a situation was attempted using leaf extract of Pergularia daemia to clear obesity by reducing the cholesterol level in the serum. Thus obesity which has a clinical effect on PCOS can be treated using the extract of the plant chosen for the present study.