reviewTop 1% cited
Targeting hepatic macrophages to treat liver diseases
Journal of Hepatology · 2017 · Vol. 66(6) · pp. 1300–1312
Frank Tacke✉(Universitätsklinikum Aachen)
Liver physiology and pathologyLiver Disease Diagnosis and TreatmentLiver Disease and TransplantationKupffer cellChemokineCCR2Hepatic stellate cellLiver injuryMacrophageCCL2MonocyteCD14Biology
MeSH terms
AnimalsCholestasisHepatitis, Viral, AnimalHomeostasisHumansKupffer CellsLiver CirrhosisLiver DiseasesLiver Neoplasms, ExperimentalMacrophagesChemical and Drug Induced Liver Injury
Funding
- Deutsche Forschungsgemeinschaft
Citations
971
FWCI
43.16
field-weighted impact
References
142
Percentile
100%
vs. same field & year
Citations per year
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References
Liver Ischemia and Reperfusion Injury: New Insights into Mechanisms of Innate—Adaptive Immune-Mediated Tissue Inflammation
American Journal of Transplantation · 2011 · 417 citations
Macrophage heterogeneity in liver injury and fibrosis
Journal of Hepatology · 2014 · 1,014 citations
Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2
American Journal of Physiology-Gastrointestinal and Liver Physiology · 2012 · 494 citations
Promotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4
Cancer Cell · 2012 · 1,289 citations
Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2
Nature Immunology · 2006 · 1,619 citations
Bacterial infections in cirrhosis: A position statement based on the EASL Special Conference 2013
Journal of Hepatology · 2014 · 890 citations
Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
Immunity · 2014 · 6,034 citations
Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation
Immunity · 2014 · 2,133 citations
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