Burn wound healing potential of Bixa orellana Linn [Bixaceae] leaf extracts on albino mice

Abstract

The use of natural remedyrnfor burn wounds is common in tropical countries such as the Philippines. Bixarnorellana of the family Bixaceae is traditionally applied to burn wounds forrnimmediate and continued relief. This research investigated the healingrnpotential of the plant on burn wounds using five replicates of mice perrntreatment as the animal model. Different preparation procedures were employed:rncrude, ethanoic and ointment. These were compared to the commercially availablernsilver sulfadiazine (SSD). Results suggest that Bixa orellana,rnregardless of preparation procedure, were effective in treating burn wounds andrnis comparable to SSD. Percent wound contraction, re-epithelialization time, andrnhistological features of the wound treated with Bixa orellana extractsrnwere comparable to the control (SSD).