review Open AccessTop 1% cited
Liquid biopsies come of age: towards implementation of circulating tumour DNA
Nature reviews. Cancer · 2017 · Vol. 17(4) · pp. 223–238
Jonathan C. M. Wan✉(Cancer Research UK)Charles Massie(Cancer Research UK Cambridge Center)Javier García-Corbacho(Hospital Clínic de Barcelona)Florent Moulière(Cancer Research UK)James D. Brenton(Cancer Research UK Cambridge Center)Carlos Caldas(Cancer Research UK Cambridge Center)Simon Pacey(Cancer Research UK Cambridge Center)Richard D. Baird(Cancer Research UK Cambridge Center)Nitzan Rosenfeld(Cancer Research UK)
Cancer Genomics and DiagnosticsLung Cancer Treatments and MutationsGenetic factors in colorectal cancerLiquid biopsyCirculating tumor DNAPersonalized medicinePrecision oncologyMedicineProfiling (computer programming)Molecular diagnosticsPrecision medicineComputational biologyInternal medicine
MeSH terms
BiopsyDNA, NeoplasmHumansMutationNeoplasm StagingNeoplasmsBiomarkers, TumorEarly Detection of CancerPrecision MedicineClonal EvolutionErbB Receptors
Funding
- AstraZeneca
- NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research
- Cancer Research UK
- National Institute for Health and Care Research
- European Commission
- Chinese University of Hong Kong
- Sociedad Española de Oncología Médica
- Hutchison Whampoa Limited
Citations
2,586
FWCI
82.65
field-weighted impact
References
235
Percentile
100%
vs. same field & year
Citations per year
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References
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Nature reviews. Cancer · 2011 · 2,859 citations
An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
Nature Medicine · 2014 · 2,220 citations
Rapid Clearance of Fetal DNA from Maternal Plasma
The American Journal of Human Genetics · 1999 · 1,143 citations
Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer
Science Translational Medicine · 2015 · 1,115 citations
Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA
Science Translational Medicine · 2012 · 1,304 citations
Noninvasive Detection of Response and Resistance in <i>EGFR</i> -Mutant Lung Cancer Using Quantitative Next-Generation Genotyping of Cell-Free Plasma DNA
Clinical Cancer Research · 2014 · 776 citations
Maternal Plasma DNA Sequencing Reveals the Genome-Wide Genetic and Mutational Profile of the Fetus
Science Translational Medicine · 2010 · 1,101 citations
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