reviewTop 10% cited

The long story of camptothecin: From traditional medicine to drugs

Bioorganic & Medicinal Chemistry Letters · 2017 · Vol. 27(4) · pp. 701–707

Emanuela Martino(University of Pavia)Serena Della Volpe(University of Pavia)Elisa Terribile(University of Pavia)Emanuele Benetti(University of Pavia)Mirena Sakaj(University of Pavia)Adriana Centamore(University of Pavia)Andrea Sala(University of Pavia)Simona Collina✉(University of Pavia)

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Cancer therapeutics and mechanisms Lung Cancer Research Studies Neuroblastoma Research and TreatmentsCamptothecinIrinotecanTopotecanTopoisomeraseChemistryAlkaloidSN-38PharmacologyDrug resistanceDrug

MeSH terms

Antineoplastic Agents, PhytogenicCamptothecinDNA Topoisomerases, Type IHumansMedicine, TraditionalNeoplasmsStructure-Activity RelationshipApoptosisCamptotheca

Citations

284

FWCI

9.18

field-weighted impact

References

Percentile

99%

vs. same field & year

Citations per year

Cited by

Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead

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References

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.

Journal of Biological Chemistry · 1985 · 2,338 citations

Topoisomerase I inhibitors: camptothecins and beyond

Nature reviews. Cancer · 2006 · 2,190 citations

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