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Relationship between Intraoperative Hypotension, Defined by Either Reduction from Baseline or Absolute Thresholds, and Acute Kidney and Myocardial Injury after Noncardiac Surgery

Anesthesiology · 2016 · Vol. 126(1) · pp. 47–65

Vafi Salmasi✉(Outcomes Research Consortium)Kamal Maheshwari(Outcomes Research Consortium)Dongsheng Yang(Outcomes Research Consortium)Edward J. Mascha(Outcomes Research Consortium)Asha Singh(Outcomes Research Consortium)Daniel I. Sessler(Outcomes Research Consortium)Andrea Kurz(Outcomes Research Consortium)

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Abstract

The associations based on relative thresholds were no stronger than those based on absolute thresholds. Furthermore, there was no clinically important interaction with preoperative pressure. Anesthetic management can thus be based on intraoperative pressures without regard to preoperative pressure.

Hemodynamic Monitoring and Therapy Cardiac, Anesthesia and Surgical Outcomes Blood Pressure and Hypertension StudiesMedicineAcute kidney injuryMean arterial pressureBlood pressureRelative riskAnesthesiaCardiologyAbsolute risk reductionInternal medicineConfidence interval

MeSH terms

AgedFemaleHumansHypotensionIntraoperative ComplicationsMaleMiddle AgedMyocardial InfarctionOhioPostoperative ComplicationsRegistriesRetrospective StudiesRisk FactorsSurgical Procedures, OperativeCohort Studies

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Intraoperative hypotension and the risk of postoperative adverse outcomes: a systematic review