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Burden of Six Healthcare-Associated Infections on European Population Health: Estimating Incidence-Based Disability-Adjusted Life Years through a Population Prevalence-Based Modelling Study

PLoS Medicine · 2016 · Vol. 13(10) · pp. e1002150–e1002150

Alessandro Cassini✉(University Medical Center Utrecht)Diamantis Plachouras✉(European Centre for Disease Prevention and Control)Tim Eckmanns(Robert Koch Institute)Muna Abu Sin(Robert Koch Institute)Hans-Peter Blank(Robert Koch Institute)Tanja Ducomble(Robert Koch Institute)Sebastian Haller(Robert Koch Institute)Thomas Harder(Robert Koch Institute)Anja Klingeberg(Robert Koch Institute)Madlen Sixtensson(Robert Koch Institute)Edward Velasco(Robert Koch Institute)Bettina Weiß(Robert Koch Institute)Piotr Kramarz(European Centre for Disease Prevention and Control)Dominique L. Monnet(European Centre for Disease Prevention and Control)Mirjam Kretzschmar(University Medical Center Utrecht)C. Suetens(European Centre for Disease Prevention and Control)

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Abstract

We estimated the EU/EEA burden of HAIs in DALYs in 2011-2012 using a transparent and evidence-based approach that allows for combining estimates of morbidity and of mortality in order to compare with other diseases and to inform a comprehensive ranking suitable for prioritization. Our results highlight the high burden of HAIs and the need for increased efforts for their prevention and control. Furthermore, our model should allow for estimations of the potential benefit of preventive measures on the burden of HAIs in the EU/EEA.

Emergency and Acute Care Studies Healthcare Policy and Management Urinary Tract Infections ManagementMedicineEuropean unionIncidence (geometry)PopulationHealth careLife expectancyEnvironmental healthDisease burden

MeSH terms

AdolescentAdultAgedAged, 80 and overAnti-Infective AgentsChildCross InfectionEuropeFemaleDisabled PersonsPersons with DisabilitiesHumansInfantInfant, NewbornMale