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The Global Burden of Latent Tuberculosis Infection: A Re-estimation Using Mathematical Modelling
PLoS Medicine · 2016 · Vol. 13(10) · pp. e1002152–e1002152
Rein M G J Houben✉(University of London)Peter J. Dodd(University of Sheffield)
Abstract
We estimate that approximately 1.7 billion individuals were latently infected with Mycobacterium tuberculosis (M.tb) globally in 2014, just under a quarter of the global population. Investment in new tools to improve diagnosis and treatment of those with LTBI at risk of progressing to disease is urgently needed to address this latent reservoir if the 2050 target of eliminating TB is to be reached.
Tuberculosis Research and EpidemiologyPneumonia and Respiratory InfectionsDiagnosis and treatment of tuberculosisMedicineLatent tuberculosisEstimationTuberculosisDemographyPopulationGlobal healthIncidence (geometry)Confidence intervalEnvironmental health
MeSH terms
Antitubercular AgentsHumansIsoniazidMycobacterium tuberculosisRiskGlobal HealthIncidencePrevalenceTuberculosis, Multidrug-ResistantLatent Tuberculosis
Funding
- Bill and Melinda Gates Foundation
- London School of Hygiene and Tropical Medicine
Citations
2,027
FWCI
103.04
field-weighted impact
References
29
Percentile
100%
vs. same field & year
Citations per year
Cited by
Oral and temporomandibular tuberculosis: A State-of-the-art literature review
International Journal of Applied Dental Sciences · 2024 · 0 citations
References
The Growing Burden of Tuberculosis
Archives of Internal Medicine · 2003 · 2,558 citations
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