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HPA axis in major depression: cortisol, clinical symptomatology and genetic variation predict cognition

Molecular Psychiatry · 2016 · Vol. 22(4) · pp. 527–536

Jennifer Keller✉(Stanford University)R Gomez(Palo Alto University)G Williams(Brigham and Women's Hospital)Anna Lembke(Stanford University)Laura C. Lazzeroni(Stanford University)Greer M. Murphy(Stanford University)Alan F. Schatzberg(Stanford University)

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Stress Responses and Cortisol Hormonal Regulation and Hypertension Tryptophan and brain disordersPsychologyGlucocorticoid receptorCognitionEffects of sleep deprivation on cognitive performanceCortisol awakening responseGlucocorticoidNeuropsychologyWorking memoryInternal medicineHydrocortisone

MeSH terms

AdultBipolar DisorderBrainCognitionCognition DisordersDepressive Disorder, MajorMajor Depressive DisorderFemaleHumansHydrocortisoneHypothalamo-Hypophyseal SystemMaleMiddle AgedPituitary-Adrenal SystemPsychotic Disorders

Citations

870

FWCI

13.60

field-weighted impact

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100%

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References

A meta-analysis of depression severity and cognitive function